I want to help you further with your question but I need more information of what exactly you need the PO Box for. Please add some more details in the comment so I can assist you further.
If you need to add the PO Box as the company's mailing address, QuickBooks will require the company's physical address.
The system currently doesn't allow a PO Box in that field. You will get the error, Physical Address cannot be a PO Box message when the system detects a physical address isn't used.