Can i cancle payroll HMRC submission so that I make changes to the payroll?

Yes, you can cancel a payroll HMRC submission in QuickBooks Online (QBO) to make changes to the payroll, ruthn. 

To do this, you need first to delete the Full Payment Submission (FPS) in QuickBooks Online Standard Payroll. To delete an FPS submission, here's how:

1. Go to Taxes, and select Payroll tax.
2. Open the FPS submission you want to delete.
3. Select the bin icon.
4. Hit Yes, remove to confirm.

To recreate a deleted FPS, you can roll back and rerun the pay run and generate a new FPS. However, please note that you can't delete just one payment within a pay run. If you delete a pay run, QuickBooks will delete all employee payments in the payroll. 

To correct an employee payment, make changes in the next pay run, and the FPS for the next pay run will reflect the updates. Before deleting an entire pay run, print out all the pay slips and reports, so you have all the information you need when you recreate the pay run. 

If you need to delete a scheduled pay run that has already been submitted to HMRC, create a new pay schedule and add employees with the same payroll ID. If that doesn't work, contact HMRC and set up employees with new payroll IDs. Alternatively, consider switching to Advanced pay for a more streamlined process. 

If you want to proceed to delete, you can refer to this article for the steps to delete a pay run and know more about what happens when you delete a pay run: Change or delete a pay run in QuickBooks Online Standard Payroll

Just in case you want to set up pay schedules and group employees based on their payment timing, please check out this article for more guidance and information: Create a pay schedules

Don't hesitate to reach out to us if you have further questions about HMRC submission in QBO. The Community is always available to help you. Best regards.