Hi I want to issue purchase order numbers to my staff is this possible with quickbooks

Let me elaborate on some details of what you want to possibly do, userinfo-rdkltd.

Are you trying to customise purchase order numbers? If so, you can definitely do that by clicking the Gear icon. Then, tick the Custom transaction number box. I've added screenshots for your visual guide:

Furthermore, learn how you can customise the appearance and layout of sales forms. Check out this article for more details: Customise Invoices, Estimates, And Sales Receipts In QuickBooks Online.

Feel free to me know if you have questions about purchase orders. I'll always be right here to help you all the time.