Trying to edit invoices I go into edit it is all greyed out if I click lots of times it highlights the box to amend but sometimes nothing happens never use to do this

Thanks for posting to the Community, @alison-finn.

Internet files may have interrupted the connection. This way, I recommend opening QuickBooks Online in an incognito/private browser. 

Private browsing mode prevents internet files from making QBO features unresponsive.

Open a supported browser and then follow this hotkey:

• Chrome: press Ctrl + Shift + N
• Firefox: press Ctrl + Shift + P
• Microsoft Edge: press Ctrl + Shift + P
• Safari: press Command + Shift + N

If you're able to edit the invoice successfully, clear your regular browser's cache. It helps load new data and boost the browser's performance. Besides, you can use another supported browser.

Please let me know or tag me (@Jovychris_A) if you need further assistance. I'm always here to help. Take care!I