Vendor Transactions in my QB is now completely wiped out, nothing shows there and I just put in an Expense item for a vendor. This used to show all my vendor purchases.

There's no recent update to vendors transaction in QuickBooks Online, @sreuter2. You can check your Audit log to see if someone might have deleted these or marked your vendor as inactive.

To begin with, missing vendor transactions can happen for few reasons, such as accidental deletion by another user or browser-related issues, or even if the vendor was marked inactive.

Here's how to check your Audit log:

1. You can go to the Gear icon.
2. Select Audit log.
3. Use the filter options to view all changes more quickly.

If you see an inactive vendor, you can make them active again.

Here's how:

1. Navigate to the Expense menu, then click the Vendors tab.
2. Select the Gear icon above the Action column. 
3. Check the Include Inactive box under Other.
4. Type the vendor's name in the search box. Note: You will know if the vendor is inactive when the (deleted) word is next to the vendor's name.
   
5. Click Make Active button.

If the vendor transactions have been deleted, you'll need to re-create them.
 

However, If there's no deleted vendor transactions or no inactive vendors, you can try troubleshooting your browser, as issues may be caused by the browser cache. Clearing your cache and Intuit-specific cookies  can help eliminate any outdated or corrupted data that could be causing the problem. As an alternative, you can also access your QuickBooks Online account using a different supported web browser.

If you have follow-up questions, feel free to leave a comment.