Yes, you can change the home currency to USD if you are subscribed to QuickBooks Online Essentials, Plus, and Advanced. I'll help you with the process from the Accounts and Settings under Home Currency.
Before doing so, make sure the Multicurrency is not turned on. It won't allow you to process the change.
Here's how to change your home currency:
Click the Gear icon at the upper right corner.
Select Account and Settings. Then, choose Advanced tab.
Go to Currency section. Then click the pencil icon.
Choose your Home Currency from drop-down arrow.
Hit the Save button. Then Done.
For future reference, I'm adding these articles about multicurrency: