Hi there, @thepartyheavenuk. I can see the importance of saving your invoices in QuickBooks Online (QBO). It's my priority to help you with the process by performing some troubleshooting steps.
To begin with, let's ensure your browser is free from the possible cache that affects QuickBooks' performance, especially when saving your invoices. For now, try to record your invoices through a private browser to see the result.
Here are the keyboard shortcuts:
Google Chrome: press Ctrl + Shift + N
Mozilla Firefox: press Ctrl + Shift + P
Safari: press Command + Shift + N
If it works, clear the cache of your main browser to remove browser history. You can also use another supported browser as an alternative.
If you're getting the same result, I'd like to know the specific error message you've received when trying to save your transactions. This way, we can look into the error and fix it immediately.